Methyl 6-chloro-4-pyrimidinecarboxylate

Methyl 6-chloro-4-pyrimidinecarboxylate - Names and Identifiers

Name	methyl 6-chloropyrimidine-4-carboxylate
Synonyms	NSC 58346 Methyl 6-chloro-4-pyrimidinecarboxylate methyl 6-chloropyrimidine-4-carboxylate 4-PyriMidinecarboxylic acid, 6-chloro-, Methyl ester
CAS	6627-22-1

Methyl 6-chloro-4-pyrimidinecarboxylate - Physico-chemical Properties

Molecular Formula	C6H5ClN2O2
Molar Mass	172.57
Density	1.372
Boling Point	271℃
Flash Point	118℃
pKa	-2.89±0.17(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C

Methyl 6-chloro-4-pyrimidinecarboxylate - Upstream Downstream Industry

Raw Materials

Methyl 6-HydroxypyriMidine-4-carboxylate
6-Oxo-3H-pyrimidine-4-carboxylic acid

Methyl 6-chloro-4-pyrimidinecarboxylate - Introduction

methyl, also known as methyl 6-chloropyrimidine-4-carboxylate, is an organic compound. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: methyl is a colorless to yellowish solid.
-Molecular formula: C7H6ClN3O2
-Molecular weight: 191.59g/mol
-Solubility: methyl L is soluble in organic solvents such as chloroform and dichloromethane, and slightly soluble in water.

Use:
-Chemical synthesis intermediates: methyl is often used as a starting material in organic synthesis to prepare other compounds, such as pesticides, drugs and dyes.
-Drug research: It is also used to synthesize and study anticancer drugs, antiviral drugs and other biologically active compounds.
-Scientific research: methyl is used for catalytic reactions, modification of pyrimidine compounds and synthesis of new compounds.

Method:
A typical method of preparing methyl I is to react 6-chloro-pyrimidine and methyl formate in the presence of sulfuric acid, formic acid and ammonium acetate.

Safety Information:
-methyll may be harmful to the human body, so corresponding safety measures need to be taken when using or handling.
-Wear appropriate respiratory protection, eye protection and protective gloves during operation.
-Avoid direct contact with skin and inhalation of dust, fumes or gases.
-When storing and handling, it should be placed in a sealed container, away from fire and oxidizing agents, and properly marked.
-During use, pay attention to personal hygiene and maintain a well-ventilated working environment.

Last Update：2024-04-09 20:49:11